At a glance
| Mark on U-100, 1 mL | Volume | at 4.17 mg/mL Zepbound 10 mg multi-dose vial | at 5 mg/mL Zepbound 2.5 mg single-dose vial | at 8.33 mg/mL Zepbound 20 mg multi-dose vial | at 10 mg/mL Zepbound 5 mg single-dose vial | at 12.5 mg/mL Zepbound 30 mg multi-dose vial | at 16.7 mg/mL Zepbound 40 mg multi-dose vial | at 20 mg/mL Zepbound 10 mg single-dose vial | at 25 mg/mL Zepbound 12.5 mg single-dose vial and 60 mg multi-dose vial |
|---|---|---|---|---|---|---|---|---|---|
| 10 units | 0.1 mL | 0.417 mg | 0.5 mg | 0.833 mg | 1 mg | 1.25 mg | 1.67 mg | 2 mg | 2.5 mg |
| 20 units | 0.2 mL | 0.834 mg | 1 mg | 1.67 mg | 2 mg | 2.5 mg | 3.34 mg | 4 mg | 5 mg |
| 25 units | 0.25 mL | 1.04 mg | 1.25 mg | 2.08 mg | 2.5 mg | 3.13 mg | 4.17 mg | 5 mg | 6.25 mg |
| 30 units | 0.3 mL | 1.25 mg | 1.5 mg | 2.5 mg | 3 mg | 3.75 mg | 5.01 mg | 6 mg | 7.5 mg |
| 40 units | 0.4 mL | 1.67 mg | 2 mg | 3.33 mg | 4 mg | 5 mg | 6.68 mg | 8 mg | 10 mg |
| 50 units | 0.5 mL | 2.08 mg | 2.5 mg | 4.17 mg | 5 mg | 6.25 mg | 8.35 mg | 10 mg | 12.5 mg |
| 60 units | 0.6 mL | 2.5 mg | 3 mg | 5 mg | 6 mg | 7.5 mg | 10.02 mg | 12 mg | 15 mg |
Arithmetic at the concentrations shown. The concentration on your own label is the one that counts; enter it in the calculator.
Why the milligrams depend on the vial
40 units is 0.4 mL. At the Zepbound concentrations that is 1.67 mg, 2 mg, 3.33 mg, 4 mg, 5 mg, 6.68 mg, 8 mg or 10 mg, depending on which vial the liquid came from. Two of those look like labelled strengths: 5 mg at 12.5 mg/mL and 10 mg at 25 mg/mL. Neither is a labelled draw. The 30 mg multi-dose vial at 12.5 mg/mL gives its 7.5 mg dose in 0.6 mL, and the 60 mg vial at 25 mg/mL gives 15 mg in 0.6 mL; taking 0.4 mL from either is a different dose from the one the label describes. This is the trap with converting marks back to milligrams: a number that happens to match a strength on the box is not evidence that the draw is correct.
The mistake to watch for. A friend's 40 units is not your 40 units. Concentrations differ between Zepbound vials and, for compounded products, between pharmacies. Compare doses in milligrams and convert each through its own label.