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Calculator/HCG

Medication

HCG reconstitution calculator

HCG is prescribed in units and the syringe is marked in units, and the two have nothing to do with each other. The liquid you add decides how many marks your dose is.

Dose to syringe mark calculator

Which chorionic gonadotropin vial do you have?Read the box or the label

Pregnyladd 10 mL
units
Novareladd 1 to 10 mL
units
Arithmetic only, not a dose recommendation. This converts the numbers you typed and nothing more. If anything here does not match your prescription or your label, stop and ask your pharmacist.
Full notice

This tool does not choose or check a medication, dose, concentration, diluent, syringe or route. It works from the numbers on your prescription and label, as you type them. A mark on a U-100 syringe is a volume, not a medication dose in units or IU. If anything here differs from what you were given, or you are unsure, do not prepare or inject: ask the prescriber or the dispensing pharmacist. No preset is a dose. Presets exist for FDA-approved products; any other vial is arithmetic on your own label.

  • Arithmetic: checked against 24 worked examples, last run 2026-09-05. See the examples
  • Vial presets: read from current FDA labels, checked 2026-09-04. Sources
  • Clinical review: none. No clinician reviews this site; the presets are read from the labels above and the result is arithmetic. Confirm every draw with your pharmacist.
  • Report a problem

One word, two meanings

A 10,000-unit vial of Pregnyl with 10 mL of diluent is 1,000 units per millilitre. A 500-unit dose from it is 0.5 mL, which is the 50 mark on a U-100 syringe. Not the 500 mark; there is no 500 mark. The syringe's units are hundredths of a millilitre, and HCG's units are a measure of activity that happens to share the word. This is the one page on the site where the same word means two things in the same sentence, so the calculator always prints the millilitres beside the mark.

Check the official label

Pregnyl label on DailyMedNovarel label on DailyMed

Every number this page uses was read from these documents on 2026-09-04. The label is the authority; if it disagrees with this page, the label wins.

What the labels say

Pregnyl 10,000 unitsWith 10 mL diluent: 1,000 units per mL.
Novarel 5,000 and 10,000 unitsLabel lists 1 mL or 10 mL, giving 5,000 / 500 or 10,000 / 1,000 units per mL.
OvidrelA fixed pre-filled syringe. Nothing to calculate.
Menopur, Gonal-fKits with their own calibrated syringes or pooled vials. Follow the kit; not offered here.

Doses on these labels are in USP units. Prescriptions often say IU; for this product treat them as the same quantity unless your pharmacist says otherwise, and enter the dose with the units toggle.

Why the volume is the whole question

The Novarel label lists two diluent volumes, and they produce draws ten times apart for the same dose.

250 units · 10,000-unit vial + 1 mL → 0.025 mL → 2.5 marks (between the 2 and 3 marks; too fine to measure reliably)
250 units · 10,000-unit vial + 10 mL → 0.25 mL → 25 marks (easy)

Your clinic's instructions should say which volume. If they do not, the question is "how many mL do I add to this vial, and how many mL is my dose?" Both answers are in millilitres, and a millilitre is the one thing you and the syringe agree on. The calculator flags a draw that is too small to read and shows the volume that would fix it.

Why there is no 500 mark

Reading the dose off the syringe as if it were the mark. 500 units of HCG at 1,000 units per mL is the 50 mark. 250 units is the 25 mark. A ten-fold error here is one zero, which is why every result on this page shows the millilitres too.

Mixing tools

Bacteriostatic water: make the four agree Diluent passport: what your label names Three clocks: which date ends first Syringe lab: can the barrel show it

Worked answers

1 mL is how many units? Any concentration chart

Two more questions

My prescription says IU. The vial says USP units. Same thing?

For chorionic gonadotropin, yes in practice: the labels use USP units and prescriptions write IU for the same quantity. If your pharmacist says otherwise for your product, follow them.

Which syringe?

Whatever your clinic dispensed, usually a U-100 insulin syringe. The 0.5 mL and 0.3 mL sizes are easier to read for small draws, and the calculator says if the draw does not fit the one you chose.